PHF6 interacts with the LMO2 complex in T-cell acute lymphoblastic leukemia

The transcriptional mediator LIM domain only 2 (LMO2) forms a large multi-protein complex together with TAL1/LYL1, HEB/E2A, LDB1 and GATA. This complex regulates transcription from the onset of hematopoietic development and during differentiation. Chromosomal rearrangements involving LMO2 and TAL1...

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Main Authors: Vesna S. Stanulović, Sarah Binhassan, Budoor A. Jaber, Shimaa Alazmi, Fatma M.B. Saleman, Sandeep Potluri, Guy Pratt, Christian Ludwig, Douglas G. Ward, Maarten Hoogenkamp
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12167
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