WISP1 drives esophageal squamous cell carcinoma progression via modulation of cancer-associated fibroblasts and immune microenvironment

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WISP1 drives esophageal squamous cell carcinoma progression via modulation of cancer-associated fibroblasts and immune microenvironment

BackgroundPrevious studies have reported abnormal expression of WNT1-inducible signaling pathway protein 1 (WISP1)/Cellular Communication Network Factor 4 (CCN4) in esophageal squamous cell carcinoma (ESCC). However, its specific significance remains unclear. To date, no in-depth research has been c...

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Bibliographic Details
Main Authors:	Zhiqiang Yi, Qiqi Zhang, Ting Tao, Xiaojia Liu, Hui Li, Xiujuan Li, Zhiqiang Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Immunology
Subjects:	WISP1 esophageal squamous cell carcinoma cancer-associated fibroblasts tumor microenvironment immune evasion extracellular matrix
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1586790/full
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