Study on Phenotypical Activity of Isoenzyme CYP3A4 in Children

The urine levels of cortisol and 6-β-hydroxycortisol in 30 healthy children were determined with high performance liquid chromatography. The activity of cytochrome P450 isoenzyme CYP3A4 was estimated by the ratio of 6-β-hydroxycortisol and cortisol. Differences in the CYP3A4 activity depended on the...

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Bibliographic Details
Main Authors: B. I. Kantemirova, A. KH. Chernysheva, A. K. Starodubtsev, D. A. Sychev
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
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Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/418
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