A mouse model of overexpression of human IL-6 by tissue-resident macrophages in the context of LPS-induced inflammation

Chronic inflammation caused by overexpression of IL-6 underlies a number of pathological conditions Mouse models of systemic chronic inflammation with overexpression of human IL-6 (hIL-6) are in demand not only in the context of studying the molecular mechanisms of inflammation, but also in assessin...

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Main Authors: N. R. Chicherina, E. A. Gorshkova, E. A. Myachev, A. S. Yakovleva, A. M. Litvinova, O. A. Namakanova, R. V. Zvartsev, S. A. Nedospasov, M. S. Drutskaya
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2024-09-01
Series:Медицинская иммунология
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Online Access:https://www.mimmun.ru/mimmun/article/view/3090
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