Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs

BackgroundMitochondria-associated membranes (MAMs) regulate cellular Ca2+ and contribute to cardiovascular disease pathogenesis. The IP3R-GRP75-VDAC1 complex is the primary MAMs pathway regulating Ca2+ flux and cardiomyocyte calcium homeostasis. Yiqi Huoxue decoction (YQHX), a Traditional Chinese Me...

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Main Authors: Yufei Li, Tianhui Du, Yunshu Zhang, Yang Lu, Xinyi Li, Weibin Xie, Shuwen Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cardiovascular Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1596757/full
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