ANGPTL3 orchestrates hepatic fructose sensing and metabolism
Summary: Fructose metabolism is linked to metabolic dysfunction-associated steatotic liver disease (MASLD), but the regulatory mechanisms governing fructose uptake remain poorly understood. Here, we demonstrate that MASLD livers exhibit increased uptake of fructose-derived carbons compared to health...
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Main Authors: | Meng Zhao, Karen Y. Linde-Garelli, Zeyuan Zhang, David Toomer, Saranya C. Reghupaty, John Isaiah Jimenez, Laetitia Coassolo, Lianna W. Wat, Daniel Fernandez, Katrin J. Svensson |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-07-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725007338 |
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