ANGPTL3 orchestrates hepatic fructose sensing and metabolism

ANGPTL3 orchestrates hepatic fructose sensing and metabolism

Summary: Fructose metabolism is linked to metabolic dysfunction-associated steatotic liver disease (MASLD), but the regulatory mechanisms governing fructose uptake remain poorly understood. Here, we demonstrate that MASLD livers exhibit increased uptake of fructose-derived carbons compared to health...

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Main Authors: Meng Zhao, Karen Y. Linde-Garelli, Zeyuan Zhang, David Toomer, Saranya C. Reghupaty, John Isaiah Jimenez, Laetitia Coassolo, Lianna W. Wat, Daniel Fernandez, Katrin J. Svensson
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
Subjects:
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725007338
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http://www.sciencedirect.com/science/article/pii/S2211124725007338

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