Dose-response mapping of bladder and rectum in prostate cancer patients undergoing radiotherapy with and without baseline toxicity correction

Dose-response mapping of bladder and rectum in prostate cancer patients undergoing radiotherapy with and without baseline toxicity correction

Background and purpose: Radiotherapy dose–response maps (DRM) combine dose-surface maps (DSM) and toxicity outcomes to identify high-risk subregions in organ-at-risk. This study assesses the impact of baseline toxicity correction on the identification of high-risk subregions in dose–response modelin...

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Main Authors: Tanuj Puri, Tiziana Rancati, Petra Seibold, Adam Webb, Eliana Vasquez Osorio, Andrew Green, Eliana Gioscio, David Azria, Marie-Pierre Farcy-Jacquet, Jenny Chang-Claude, Alison Dunning, Maarten Lambrecht, Barbara Avuzzi, Dirk de Ruysscher, Elena Sperk, Ana Vega, Liv Veldeman, Barry Rosenstein, Jane Shortall, Sarah Kerns, Christopher Talbot, Andrew P. Morris, Alan McWilliam, Peter Hoskin, Ananya Choudhury, Catharine West, Marcel van Herk
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Physics and Imaging in Radiation Oncology
Subjects:
Prostate cancer
Radiotherapy
VBA
IBDM
Dose-toxicity modeling
Organ-at-risk
Online Access:http://www.sciencedirect.com/science/article/pii/S2405631625001101
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