Case report: A young woman with acute peri‑myocarditis and acute myeloid leukaemia with myelodysplasia-related changes
Background: Clinical presentation in acute myeloid leukaemia (AML) can result in a wide variety of clinical phenotypes. Case Report: We report the case of a 34-year-old woman who presented with severe peri‑myocarditis and concomitant AML. The patient was treated with 5-azacitidine and venetoclax fol...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | Leukemia Research Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213048925000299 |
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| Summary: | Background: Clinical presentation in acute myeloid leukaemia (AML) can result in a wide variety of clinical phenotypes. Case Report: We report the case of a 34-year-old woman who presented with severe peri‑myocarditis and concomitant AML. The patient was treated with 5-azacitidine and venetoclax followed by haploidentical allogenic haematopoetic stem cell transplantation. Unfortunately, the patient developed febrile neutropenia and died because of overwhelming neutropenic sepsis. On autopsy, no evidence of AML was identified neither in bone marrow nor in cardiac tissue. Conclusion: With this case report, we would like to emphasize the possibility of cardiac involvement in AML as well as the potential application of novel therapeutic agents in AML patients unfit for intensive chemotherapy. |
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| ISSN: | 2213-0489 |