Morphological and Molecular Evaluation of a Gel Based on Hyaluronic Acid and Spermidine for Oral Regenerative Purposes

Morphological and Molecular Evaluation of a Gel Based on Hyaluronic Acid and Spermidine for Oral Regenerative Purposes

Background: Oral wound healing is a complex process influenced by extracellular matrix (ECM) remodeling and cellular migration. Hyaluronic acid (HA) and spermidine (SP) have shown regenerative potential, but their combined effects on oral tissues remain unexplored. This study aimed to characterize t...

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Main Authors: Dolaji Henin, Elena Canciani, Daniela Carmagnola, Stefano Ferrero, Gaia Pellegrini, Mariachiara Perrotta, Riccardo Sirello, Claudia Dellavia, Nicoletta Gagliano
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
hyaluronic acid
spermidine
oral wound healing
gingival fibroblasts
organotypic cultures
ECM remodeling
Online Access:https://www.mdpi.com/2073-4409/14/14/1047
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https://www.mdpi.com/2073-4409/14/14/1047

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