PATHOGENESIS OF COLD ISCHEMIA IN CORONARY PATIENTS

Biologically relevant structural changes in cell membranes (on an RBC model) at cold test, promoting its stabilization, has a pattern of pathology in coronary patients as taking place in membranes altered by atherogenesis. Profound changes in the lipid bilayer are followed by changes in intracardiac...

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Bibliographic Details
Main Authors: A. P. Vasilyev, N. N. Streltsova, Y. N. Senatorov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2002-10-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/1887
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Summary:Biologically relevant structural changes in cell membranes (on an RBC model) at cold test, promoting its stabilization, has a pattern of pathology in coronary patients as taking place in membranes altered by atherogenesis. Profound changes in the lipid bilayer are followed by changes in intracardiac hemodynamics such as myocardial hyperfunction on one side and diastolic dysfunction with altered perfusion on the other side. These physiologically opposite tendencies may lie behind stress cold ischemia in coronary patients.
ISSN:1560-4071
2618-7620