Physical and Chemical Inactivators Evaluation for the Puumala Virus Vaccine Technology Development

Physical and Chemical Inactivators Evaluation for the Puumala Virus Vaccine Technology Development

Relevance. Hemorrhagic fever with renal syndrome (HFRS) is leading among natural focal human diseases in Russia, the causative agents of which - orthohantaviruses - belong to the order Bunyavirales, family Hantaviridae. More than 98% of HFRS cases in Russia are caused by the Puumala virus. It is a s...

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Main Authors: S. S. Kurashova, M. S. Egorova, M. V. Balovneva, A. N. Vetrova, A. S. Balkina, R. D. Teodorovich, V. G. Petrov, T. K. Dzagurova, E. A. Tkachenko
Format: Article
Language:Russian
Published: Numikom LLC 2024-09-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
hemorrhagic fever with renal syndrome
inactivated vaccines
β-propiolactone
hydrogen peroxide
ultraviolet radiation
gamma irradiation
thermal activation
Online Access:https://www.epidemvac.ru/jour/article/view/2049
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