Caloric restriction mimetics chlorogenic acid and fisetin as potential autophagy inducers targeting ATG101

Autophagy is an important cytoprotective process impaired in neurodegenerative diseases such as Alzheimer's disease. The initiation process is mediated by the protein kinase Unc-51-like kinase 1 (ULK1) complex. ATG101, a cytosolic protein, plays a pivotal role in initiating autophagy as a compo...

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Bibliographic Details
Main Authors: Apoorv Sharma, Indu Kumari, Asimul Islam, Hridayesh Prakash, Amresh Prakash, Vijay Kumar
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Biochemistry and Biophysics Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405580825001682
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