Hernandezine induces autophagic cell death in hepatocellular carcinoma cells via the AMPK/mTOR signaling pathway

Hernandezine induces autophagic cell death in hepatocellular carcinoma cells via the AMPK/mTOR signaling pathway

Objective To investigate the autophagy activation effect of hernandezine (HER) on hepatocellular carcinoma (HCC) cells and its role in inducing autophagic cell death. Methods The inhibitory effects of HER on the proliferation of HCC cell lines Hep 3B and Huh-7 were assessed using CCK-8 assay. HCC c...

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Bibliographic Details
Main Author: WANG Jun, HU Gangfeng, GAO Weichen, WANG Lubing
Format: Article
Language:Chinese
Published: Editorial Office of Journal of Surgery Concepts & Practice 2025-03-01
Series:Waike lilun yu shijian
Subjects:
|hepatocellular carcinoma(hcc)|hernandezine(her)|adenosine 5'-monophosphate(amp)-activated protein kinase(ampk)/mammalian target of rapamycin(mtor)|autophagic cell death
Online Access:https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1751876771873-1840566956.pdf
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