SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.

SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.

The COVID-19 pandemic is caused by the enveloped virus SARS-CoV-2. Despite extensive investigation, the molecular mechanisms for its assembly and secretion remain largely elusive. Here, we show that SARS-CoV-2 infection induces global alterations of the host endomembrane system, including dramatic G...

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Main Authors: Jianchao Zhang, Andrew Kennedy, Daniel Macedo de Melo Jorge, Lijuan Xing, Whitney Reid, Sarah Bui, Joseph Joppich, Molly Rose, Sevval Ercan, Qiyi Tang, David Ginsburg, Andrew W Tai, Yanzhuang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013295
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https://doi.org/10.1371/journal.ppat.1013295

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