Dynamic imaging of myelin pathology in physiologically preserved human brain tissue using third harmonic generation microscopy.

Myelin pathology is known to play a central role in disorders such as multiple sclerosis (MS) among others. Despite this, the pathological mechanisms underlying these conditions are often difficult to unravel. Conventional techniques like immunohistochemistry or dye-based approaches, do not provide...

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Bibliographic Details
Main Authors: Niels R C Meijns, Max Blokker, Sander Idema, Bert A 't Hart, Mitko Veta, Loes Ettema, Juliet van Iersel, Zhiqing Zhang, Geert J Schenk, Marie Louise Groot, Antonio Luchicchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0310663
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