Bicarbonate-buffered solution versus Plasma-Lyte in orthotopic adult liver transplantation: a pilot open-label, randomized, non-inferiority trial

Bicarbonate-buffered solution versus Plasma-Lyte in orthotopic adult liver transplantation: a pilot open-label, randomized, non-inferiority trial

Background The ideal intravenous maintenance and resuscitation fluid for patients undergoing orthotopic liver transplantation (OLT) remains unknown. We aimed to determine whether bicarbonate-buffered solution was non-inferior to Plasma-LyteTM in preventing metabolic acidosis during OLT. Methods We c...

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Main Authors: Fumitaka Yanase, Laurence Weinberg, Michael Jiang, Varun Peri, Rebecca Caragata, Jian Wen Chan, Lachlan F. Miles, Shervin Tosif, Louise Ellard, Peter McCall, Brett Pearce, David A. Story, Param Pillai, Antony Leaver, Hannah Perlman, Jinesh Patel, Glenn Eastwood, Dong Kyu Lee, Rinaldo Bellomo
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2025-08-01
Series:Korean Journal of Anesthesiology
Subjects:
anesthesia
bicarbonate
crystalloid solutions
liver transplantation
randomized controlled trial
resuscitation
Online Access:http://ekja.org/upload/pdf/kja-24677.pdf
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