Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method

BackgroundAlzheimer’s disease (AD) is marked by the pathological features of amyloid-β plaque accumulation, as well as intracellular neurofibrillary tangles formation in the patients’ brain. Aberrant lipid metabolism is increasingly recognized as one of the important contributors to AD.PurposeThe ma...

Full description

Saved in:
Bibliographic Details
Main Authors: Shiyu Xiao, Xuemeng Wei, Bing Han, Xiaoqian Shi, Congzhen Wei, Rumeng Liang, Jingna Sun, Zheng Zhang, Zhengang Han, Li Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1561831/full
Tags: Add Tag
No Tags, Be the first to tag this record!