Synthesis of 2-Halo-3-Formylindoles via Vilsmeier–Haack Haloformylation Reaction of Oxindole
A series of 2-halo-3-formylindole molecules were synthesized via Vilsmeier–Haack haloformylation reaction of N-Boc-oxindole with POCl3 or POBr3 and DMF, which are free from the use of catalyst and solvent. Moreover, through several simple postprocessing steps, corresponding adducts can be readily tr...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/joch/8562391 |
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