Phenomenon of loss of heterozygosity in tumour tissue of breast cancer: association with expression of monoresistance genes

Purpose of work. To perform a genome-wide association study of loss of heterozygosity (LOH) with monoresistance genes expression during neoadjuvant chemotherapy (NAC) in breast cancer.Materials and methods. The study involved 68 patients with breast cancer. The tumour stages were IIAIIIB. RNA was ex...

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Main Authors: M. M. Tsyganov, I. V. Deryusheva, E. Yu. Garbukov, M. K. Ibragimova, P. V. Kazantseva, V. A. Bychkov, E. M. Slonimskaya, N. V. Litviakov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2018-01-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/1042
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