Quantitation of polysorbate 80 in recombinant protein formulation using high-performance liquid chromatography

Objectives. Polysorbate 80 (PS80) quantification in biopharmaceutical products has always been challenging owing to its minute content, absorption to the protein backbone, lack of specific chromophoric PS80 groups, and heterogenic nature. This work is aimed at developing an express method for PS80 a...

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Bibliographic Details
Main Authors: A. D. Askretkov, D. O. Shatalov, N. V. Orlova, D. I. Zybin, V. V. Nikolaeva, A. A. Klishin, E. S. Tuzova, D. S. Minenkov, S. A. Kedik, Yu. A. Seregin
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2022-04-01
Series:Тонкие химические технологии
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Online Access:https://www.finechem-mirea.ru/jour/article/view/1798
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