Prevalence of intestinal metaplasia, dysplasia, and esophageal adenocarcinoma in patients with irregular Z-line: a systematic review and meta-analysis

Background/Aims The irregular Z-line, defined as a segment of columnar mucosa less than 1 cm in the distal esophagus, is often biopsied despite guidelines advising against it due to a low risk of progression to esophageal adenocarcinoma (EAC). However, the clinical significance of an irregular Z-lin...

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Bibliographic Details
Main Authors: Vishali Moond, Pradeep Yarra, Mannat Bhatia, Sheza Malik, Vineel Malavarappu, Hassam Ali, Saurabh Chandan, Douglas G. Adler, Babu P. Mohan
Format: Article
Language:English
Published: Korean Society of Gastrointestinal Endoscopy 2025-05-01
Series:Clinical Endoscopy
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Online Access:http://e-ce.org/upload/pdf/ce-2024-211.pdf
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