Sirtuin 6 plays an oncogenic role and induces cell autophagy in esophageal cancer cells
Sirtuin 6, a member of sirtuin family, is generally regarded as a tumor suppressor as it participates in suppressing hypoxia-inducible factor 1α and MYC transcription activity by deacetylating H3K9 (histone H3 lysine 9) and H3K56 (histone H3 lysine) at promoters of target genes, leading to the aerob...
Saved in:
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-06-01
|
Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317708532 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|