Micro-/nano-structured zirconia surface promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by reducing pyroptosis under inflammatory conditions

Background/purpose: Promoting osteogenesis under inflammatory conditions holds promise for preventing and mitigating peri-implantitis. Cell pyroptosis inhibits osteoblast-mediated bone formation. Although the surface topography of implant materials influences both osteogenesis and inflammatory respo...

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Bibliographic Details
Main Authors: Hui-Min Wang, Qian Ding, Ying Chen, Yao-Jun Zhang, Zhi-Xiao Wu, Xiao Zhang, Lei Zhang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Journal of Dental Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790225000443
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