A novel mesothelioma molecular classification based on malignant cell differentiation

A novel mesothelioma molecular classification based on malignant cell differentiation

Abstract Background The high heterogeneity and multi-directional poor differentiation of tumor cells in mesothelioma (MESO) contributes to tumor growth and malignant biological behaviors. However, a molecular classification based on differentiated states of tumor cells remains void. Methods We perfo...

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Main Authors: Jun Liu, Yifan Liu, Yuwei Lu, Wei Zhang, Jiale Yan, Bingnan Lu, Yuntao Yao, Shuyuan Xian, Donghao Lyu, Jiaying Shi, Yuanan Li, Xinru Wu, Chenguang Bai, Jie Zhang, Yuan Zhang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
Subjects:
Mesothelioma (MESO)
Single-cell RNA sequencing (scRNA-seq)
Tumor heterogeneity
Gene classification
Prognostic prediction model
Online Access:https://doi.org/10.1186/s12935-025-03816-9
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https://doi.org/10.1186/s12935-025-03816-9

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