Effect of the main metabolite of afobazole M-11 on acute exudative inflammation and visceral pain in mice

In the model of peritonitis in mice induced by intraperitoneal injection of acetic acid the main metabolite of afobazole M-11 at doses of 1, 5 and 10 mg/kg per os reduces the intensity of the exudative stage of inflammation, but at doses of 20 and 40 mg/kg it exhibits no anti-inflammatory activity....

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Bibliographic Details
Main Authors: E. A. Ivanova, T. A. Voronina
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2016-03-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
Online Access:https://www.pharmacokinetica.ru/jour/article/view/174
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