Enhancing targeted delivery and efficacy of PEGylated liposomal doxorubicin with liposomal minoxidil: comprehensive in silico, in vitro, and in vivo tumor model studies
The therapeutic efficacy of nanoparticle (NP)-encapsulated cytotoxic drugs has remained limited by poor penetration into solid tumors. To address this challenge, we developed a novel strategy using minoxidil-loaded nanoliposomes (Lip-MXD) to induce tumor vasodilation and enhance the delivery of PEGy...
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Main Authors: | Vahideh Mohammadzadeh, Leila Arabi, Seyedeh Maryam Hosseinikhah, Mohammad Mashreghi, Fatemeh Kalalinia, Neda Mostajeran, Mohammad Reza Zirak, Farzin Hadizadeh, Mojgan Nejabat, Hossein Kamali, Niloufar Rahiman, Mahmoud Reza Jaafari |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2025-12-01
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Series: | Drug Delivery |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/10717544.2025.2536802 |
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