<i>Pseudorabies Virus</i> IE180 Inhibits Virus Replication by Activating the Type I Interferon Pathway

<i>Pseudorabies Virus</i> IE180 Inhibits Virus Replication by Activating the Type I Interferon Pathway

The immediate-early protein IE180 of <i>pseudorabies virus</i> (PRV) is a multifunctional regulator of viral and host gene expression. However, its role in modulating antiviral immune responses remains poorly understood. Here, we demonstrate that IE180 overexpression significantly inhibi...

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Bibliographic Details
Main Authors: Feiyang Zheng, Jingjing Song, Xuan Chen, Dongyue Xing, Rulan Bai, Changyong Cheng, Jin Yuan, Rui Zhang
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Microorganisms
Subjects:
<i>pseudorabies virus</i>
IE180
type I interferon pathway
antiviral immunity
Online Access:https://www.mdpi.com/2076-2607/13/6/1397
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https://www.mdpi.com/2076-2607/13/6/1397

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