CaF2 nanoparticles deliver siRNA targeting STAT6 and PPAR- γ to depolarise tumour-associated macrophages

Breast cancer is a leading cause of death in women, partly due to challenges posed by constituents of the tumour-microenvironment, such as tumour-associated macrophages (TAMs). Polarisation of macrophages to a pro-tumour phenotype usually involves STAT6 and PPAR- γ pathways. In this study, CaF2 nano...

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Bibliographic Details
Main Authors: Hamed Al-Busaidi, Won Fen Wong, Lakshmi Selvaratnam, Ezharul Hoque Chowdhury
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:BBA Advances
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Online Access:http://www.sciencedirect.com/science/article/pii/S266716032500033X
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