Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions? A systematic review

Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions? A systematic review

Autophagy is a key regulator of cellular homeostasis and neuronal survival, particularly under adverse physiological conditions. Environmental enrichment (EE), a non-pharmacological intervention providing enhanced sensory, cognitive, and motor stimulation, may modulate autophagic processes in the br...

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Main Authors: Clarice Beatriz Gonçalves Silva, Matheus Santos de Sousa Fernandes, Debora Dantas Nucci Cerqueira, Gabriela Carvalho Jurema Santos, Fatma Hilal Yagin, Yalin Aygun, Georgian Badicu, Fabiana S. Evangelista, Pablo Prieto-González, Fabrício Oliveira Souto, Ashit Kumar Dutta, Sameer Badri Al-Mhanna, Abedelmalek Kalefh Tabnjh
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
enriched environment
cellular autophagy
central nervous system
metabolism
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2025.1624500/full
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https://www.frontiersin.org/articles/10.3389/fncel.2025.1624500/full

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