Mature megakaryocytes acquire immune characteristics in a mouse model of aplastic anemia

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Mature megakaryocytes acquire immune characteristics in a mouse model of aplastic anemia

Abstract: Megakaryocytes (MKs) serve diverse roles beyond platelet production, including hematopoietic stem cell maintenance and immune response modulation. In our mouse model of immune bone marrow failure (BMF), we observed the unexpected persistence of MKs despite thrombocytopenia. These MKs exhib...

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Bibliographic Details
Main Authors:	Ashvind Prabahran, Liangliang Wu, Ash Lee Manley, Zhijie Wu, Shouguo Gao, Hiroki Mizumaki, Valentina Baena, Zulfeqhar Syed, Christian A. Combs, Jichun Chen, Xingmin Feng, Neal S. Young
Format:	Article
Language:	English
Published:	Elsevier 2025-07-01
Series:	Blood Advances
Online Access:	http://www.sciencedirect.com/science/article/pii/S2473952925001557
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