THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS
Purpose: the features of the innate and adaptive immunity of patients with multiple sclerosis was investigated. Materials and methods: the results of flow cytometry, reaction of blast transformation of lymphocytes,immunosorbent assay and other parameters of innate immunity of 85 patients with multip...
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2016-06-01
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| Series: | Медицинский вестник Юга России |
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| Online Access: | https://www.medicalherald.ru/jour/article/view/365 |
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| author | I. I. Andreevа L. P. Sizyakina Z. A. Goncharova |
| author_facet | I. I. Andreevа L. P. Sizyakina Z. A. Goncharova |
| author_sort | I. I. Andreevа |
| collection | DOAJ |
| description | Purpose: the features of the innate and adaptive immunity of patients with multiple sclerosis was investigated. Materials and methods: the results of flow cytometry, reaction of blast transformation of lymphocytes,immunosorbent assay and other parameters of innate immunity of 85 patients with multiple sclerosis was investigated. Results: It is determined that the factors of innate immunity play a significant role in the pathogenesis of multiple sclerosis. We can see the evaluation of suchimmunogenesis stages as recognition, activation, proliferation, differentiation of immune cells. Summary: all stages of the immune response were disturbed during exacerbation of multiple sclerosis. The antigen recognition processes are restored with the remission of this disease. The stages of the activation, proliferation and differentiation of immune cells were without changes. |
| format | Article |
| id | doaj-art-726b35e6f5d44ce1b5bc17e18a2b7ed7 |
| institution | Matheson Library |
| issn | 2219-8075 2618-7876 |
| language | English |
| publishDate | 2016-06-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Медицинский вестник Юга России |
| spelling | doaj-art-726b35e6f5d44ce1b5bc17e18a2b7ed72025-07-03T16:13:38ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762016-06-0102232710.21886/2219-8075-2016-2-23-27319THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSISI. I. Andreevа0L. P. Sizyakina1Z. A. Goncharova2Rostov State Medical University, 29 Nakhichevansky st., Rostov-on-Don, 344022, RussiaRostov State Medical University, 29 Nakhichevansky st., Rostov-on-Don, 344022, RussiaRostov State Medical University, 29 Nakhichevansky st., Rostov-on-Don, 344022, RussiaPurpose: the features of the innate and adaptive immunity of patients with multiple sclerosis was investigated. Materials and methods: the results of flow cytometry, reaction of blast transformation of lymphocytes,immunosorbent assay and other parameters of innate immunity of 85 patients with multiple sclerosis was investigated. Results: It is determined that the factors of innate immunity play a significant role in the pathogenesis of multiple sclerosis. We can see the evaluation of suchimmunogenesis stages as recognition, activation, proliferation, differentiation of immune cells. Summary: all stages of the immune response were disturbed during exacerbation of multiple sclerosis. The antigen recognition processes are restored with the remission of this disease. The stages of the activation, proliferation and differentiation of immune cells were without changes.https://www.medicalherald.ru/jour/article/view/365multiple sclerosismmunogenesisstages |
| spellingShingle | I. I. Andreevа L. P. Sizyakina Z. A. Goncharova THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS Медицинский вестник Юга России multiple sclerosis mmunogenesisstages |
| title | THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS |
| title_full | THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS |
| title_fullStr | THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS |
| title_full_unstemmed | THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS |
| title_short | THE INVERSION OF HOMEOSTATIC PROPERTIES OF THE IMMUNE SYSTEM IN PATIENTS WITH MULTIPLE SCLEROSIS |
| title_sort | inversion of homeostatic properties of the immune system in patients with multiple sclerosis |
| topic | multiple sclerosis mmunogenesisstages |
| url | https://www.medicalherald.ru/jour/article/view/365 |
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