Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development
Orofacial clefts are the second-most prevalent congenital malformation. Risk factors are multifactorial and include genetic components, but also environmental factors. One environmental factor is hypoxia during pregnancy, caused for instance by tobacco smoking, medication or living at high altitudes...
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Main Authors: | Theresa Schmid, Gabriele Rodrian, Elke Bachmann, Alexander Kohler, Michael Wegner, Lina Gölz, Matthias Weider |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2025-07-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.250129 |
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