Osteoblasts sense extracellular levels of phosphate to control the local expression of phosphatases for matrix mineralisation
The provision of inorganic phosphate (Pi) for biomineralisation is under systemic and local control. Locally, osteoblast production of phosphatases such as tissue-nonspecific alkaline phosphatase (TNAP) and PHOSPHO1 is required for normal skeletal mineralisation and osteoblasts may sense extracellul...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-09-01
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Series: | Bone Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352187225000403 |
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