Genome mining identifies a diversity of natural product biosynthetic capacity in human respiratory Corynebacterium strains

Genome mining identifies a diversity of natural product biosynthetic capacity in human respiratory Corynebacterium strains

ABSTRACT Corynebacterium species, integral to the healthy human upper respiratory tract (URT) microbiota, remain underexplored in microbial genomics for their potential to promote respiratory health and exclude pathobionts. This genomic study investigated the diversity and capacity for natural produ...

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Main Authors: Ashley L. Cunningham, Ilya Y. Zhbannikov, Rachel Myers, Tommy H. Tran, Wei Gao, Katherine P. Lemon, Jhoanna N. Aquino, Jillian H. Hurst, Joon Won Yoon, Patrick C. Seed, Matthew S. Kelly
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mSphere
Subjects:
upper respiratory tract
bacteriocins
whole-genome sequencing
human microbiota
microbiome
biosynthetic gene clusters
Online Access:https://journals.asm.org/doi/10.1128/msphere.00258-25
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https://journals.asm.org/doi/10.1128/msphere.00258-25

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