High-fat diet-induced increase in glucocorticoids contributes to adipogenesis in obese mice

High-fat diet-induced increase in glucocorticoids contributes to adipogenesis in obese mice

Background: This study was designed to examine how glucocorticoids (GCs) induced by a long-term ingestion of high-fat diet (HFD) mediate the HFD-induced adipose expansion and obesity. Material and methods: To address this goal, we used a unique L/L mouse model that fails to induce its corticosterone...

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Bibliographic Details
Main Authors: Sheng-Feng Tsai, Pei-Ling Hsu, Mei-Chen Yeh, Hao-Chang Hung, Monica Meng-Chun Shih, Bon-chu Chung, Chia-Yih Wang, Chih-Jen Chang, Yu-Min Kuo
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Biomedical Journal
Subjects:
Corticosterone
Adipose expansion
Adipogenesis
Obesity
Pref-1
Diet-induced obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417024000751
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http://www.sciencedirect.com/science/article/pii/S2319417024000751

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