Decoding Secondary Motor Cortex Neuronal Activity During Cocaine Self-Administration: Insights From Longitudinal In Vivo Calcium Imaging

Decoding Secondary Motor Cortex Neuronal Activity During Cocaine Self-Administration: Insights From Longitudinal In Vivo Calcium Imaging

Background: We recently reported that cocaine relapse risk is linked to hyperexcitability in the secondary motor cortex (M2) after prolonged withdrawal following intravenous self-administration (IVSA). However, the neuronal mechanisms underlying drug-taking behaviors and the response of M2 neurons t...

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Bibliographic Details
Main Authors: Yingying Chen, Haoying Fu, Amith Korada, Michal A. Lange, Chandrashekar Rayanki, Tao Lu, Dongbing Lai, Shiaofen Fang, Changyong Guo, Yao-Ying Ma
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Biological Psychiatry Global Open Science
Subjects:
Calcium transient
Cocaine
Drug taking
In vivo Ca2+ imaging
Intravenous self-administration
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667174325000850
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