Empagliflozin attenuates ventricular fibrillation postmyocardial infarction associated with reduced transforming growth factor-1/Smad3 signaling and miR-181a expression

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Empagliflozin attenuates ventricular fibrillation postmyocardial infarction associated with reduced transforming growth factor-1/Smad3 signaling and miR-181a expression

Objective To determine whether empagliflozin reduces ventricular fibrillation and myocardial fibrosis after myocardial infarction via the transforming growth factor-β1/Smad3/miR-181a pathway. Methods Male nondiabetic Sprague–Dawley rats (n = 16) were randomized into sham, myocardial infarction, low-...

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Bibliographic Details
Main Authors:	Jingsong Shen, Min Huang, Zixu Ye, Yuling Jing, Ziyang Yuan, Zeming Xiang, Miao Ding, Tao Li, Qiang Ye
Format:	Article
Language:	English
Published:	SAGE Publishing 2025-07-01
Series:	Journal of International Medical Research
Online Access:	https://doi.org/10.1177/03000605251353040
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