Empagliflozin attenuates ventricular fibrillation postmyocardial infarction associated with reduced transforming growth factor-1/Smad3 signaling and miR-181a expression
Objective To determine whether empagliflozin reduces ventricular fibrillation and myocardial fibrosis after myocardial infarction via the transforming growth factor-β1/Smad3/miR-181a pathway. Methods Male nondiabetic Sprague–Dawley rats (n = 16) were randomized into sham, myocardial infarction, low-...
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Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2025-07-01
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Series: | Journal of International Medical Research |
Online Access: | https://doi.org/10.1177/03000605251353040 |
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