Change in Gasdermin-D gene expression in familial Mediterranean fever compared to healthy children with or without acute infections
Background. Gasdermin-D (GSDMD) is an inflammasome regulator. Pyroptosis and GSDMD-mediated interleukin (IL)-1β secretion abolish in GSDMD-deficient familial Mediterranean fever (FMF) knock-in mice. We aimed to investigate GSDMD gene expression (GSDMD-∆), acute phase reactants (APRs), serum IL-1β,...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hacettepe University Institute of Child Health
2025-07-01
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Series: | The Turkish Journal of Pediatrics |
Subjects: | |
Online Access: | https://turkjpediatr.org/article/view/5389 |
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