FTO‐mediated m6A demethylation regulates IGFBP3 expression and AKT activation through IMP3‐dependent P‐body re‐localisation in lung cancer

Abstract Lung cancer remains one of the leading causes of cancer‐related deaths worldwide, and a growing body of evidence suggests that RNA modifications, including methylation, play a critical role in its progression. In this study, we investigated the role of the RNA demethylase fat mass and obesi...

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Bibliographic Details
Main Authors: Haiyang Wang, Hui Peng, Zhenzhen Zhang, Yilimunuer Abulimiti, Jiayi Hu, Yongxin Zhou, Ping Ji, Dong Li
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Clinical and Translational Medicine
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Online Access:https://doi.org/10.1002/ctm2.70392
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