Regulation of Mitochondrial Metabolism by <i>Mfn1</i> Gene Encoding Mitofusin Affects Cellular Proliferation and Histone Modification

Regulation of Mitochondrial Metabolism by <i>Mfn1</i> Gene Encoding Mitofusin Affects Cellular Proliferation and Histone Modification

Mitochondria maintain cellular homeostasis through the dynamic balance of fusion and fission, which relies on nuclear-encoded mitochondrial fusion proteins, mitofusins 1 and 2 (Mfn1, Mfn2). Changes in <i>Mfn1</i> and <i>Mfn2</i> expression significantly affect mitochondrial f...

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Bibliographic Details
Main Authors: Han Xu, Xiaoyu Zhao, Yuan Yun, Yuxin Gao, Chunjie Bo, Lishuang Song, Chunling Bai, Lei Yang, Guangpeng Li, Guanghua Su
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
mitochondrial dynamics
<i>Mfn1</i>
mitochondrial metabolism
cell proliferation
epigenetic modifications
Online Access:https://www.mdpi.com/2073-4409/14/13/1015
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https://www.mdpi.com/2073-4409/14/13/1015

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