Search of the correlation berween anxiolytic effect of original derivative of pyrrolo [1,2-A] pyrazine TSPO-LIGAND (GML-1) and its concentrations in the rat blood plasma

Resume. Comparison of “concentration-effect” relation for a new potential anxiolytic drug GML-1, being TSPO Ligand was carried out. GML-1 was administered in rats once, intragastricaLLy in the dose 1 mg/kg. Tested drug concentrations in the rat bLood plasma and animaLs behavior in the test of “eLeva...

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Bibliographic Details
Main Authors: M. A. Yarkova, A. A. Litvin, G. B. Kolyvanov, V. P. Zherdev, S. B. Seredenin, V. I. Gegechkori
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2018-03-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
Online Access:https://www.pharmacokinetica.ru/jour/article/view/60
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