Overcoming Immune Barriers in Allogeneic CAR-NK Therapy: From Multiplex Gene Editing to AI-Driven Precision Design
Chimeric antigen receptor (CAR)-engineered natural killer (NK) cells are a promising platform for off-the-shelf immunotherapy due to their safety advantages over CAR-T cells, including lower risk of graft-versus-host disease, cytokine release syndrome, and neurotoxicity. However, their persistence a...
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Format: | Article |
Language: | English |
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MDPI AG
2025-06-01
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Series: | Biomolecules |
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Online Access: | https://www.mdpi.com/2218-273X/15/7/935 |
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