The pan-variant potential of light: 425 nm light inactivates SARS-CoV-2 variants of concern and non-cytotoxic doses reduce viral titers in human airway epithelial cells

The pan-variant potential of light: 425 nm light inactivates SARS-CoV-2 variants of concern and non-cytotoxic doses reduce viral titers in human airway epithelial cells

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) prolonged the coronavirus disease 2019 (COVID-19) pandemic. The continued development of novel pan-variant therapeutics to treat currently circulating and future VOCs is critically important. Photomedici...

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Main Authors: Nathan Stasko, Leslee Arwood, Nicole Jandick, Derry Spragion, Rachel C. Roberts, Mónica Setién, Ibrahim Henson, Abigail Annas, M. Leslie Fulcher, Marisa Brotton, Larry Kummer, Frank Szaba, Matt Reagan, Kathleen Lanzer, Tres Cookenham, Sean Casey, Nagarama Kothapalli, Tricia Hart, Shelton S. Bradrick, David Emerson, Adam S. Cockrell, Scott H. Randell, Jacob F. Kocher
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mSphere
Subjects:
coronavirus
photomedicine
antiviral agents
Online Access:https://journals.asm.org/doi/10.1128/msphere.00230-25
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https://journals.asm.org/doi/10.1128/msphere.00230-25

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