Impact of first-line chemoimmunotherapy with or without radiotherapy on the prognosis of patients with locally advanced or metastatic esophageal squamous cell carcinoma: a multicenter, real-world, retrospective cohort study from China (NCT06478355)

Impact of first-line chemoimmunotherapy with or without radiotherapy on the prognosis of patients with locally advanced or metastatic esophageal squamous cell carcinoma: a multicenter, real-world, retrospective cohort study from China (NCT06478355)

BackgroundChemotherapy combined with immunotherapy has already become the standard first-line treatment for advanced or metastatic esophageal squamous cell carcinoma (ESCC), whereas there are no satisfying overall survival (OS) and progression-free survival (PFS). This research aims to evaluate whet...

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Main Authors: Xinyi Liu, Jingyuan Wen, Yaowen Zhang, Chenyu Wang, Yatian Liu, Pudong Qian, Jianzhong Cao, Qing Hou, Yuanji Xu, Zhongmei Lin, Xianghua Ye, Min Hou, Yan Gui, Lulu Wang, Wei Zhou, Zhimin Zeng, Yaqi Song, Honglei Luo, Jiahua Lv, Wenbin Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
esophageal squamous cell carcinoma
radiotherapy
immunotherapy
chemotherapy
real-world data
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1633930/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1633930/full

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