Anterior insular cortex glutamate-glutamine (Glx) levels predict general psychopathology via heightened error sensitivity
IntroductionThe anterior insular cortex (AIC) integrates interoceptive, cognitive-emotional, and error-monitoring signals, and is consistently hyperactive in anxiety and depression. Converging evidence links elevated glutamate + glutamine (Glx) in fronto-insular regions to stress reactivity; however...
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Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2025.1592015/full |
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