Paradoxical Antidepressant Effects of Sleep Deprivation in Depression: Mechanisms, Clinical Effects, and Therapeutic Implications

Paradoxical Antidepressant Effects of Sleep Deprivation in Depression: Mechanisms, Clinical Effects, and Therapeutic Implications

Introduction and purpose: Sleep deprivation (SD), paradoxically, has been shown to induce rapid antidepressant effects in patients with depressive disorders. This review explores the neurobiological underpinnings, clinical efficacy, and therapeutic strategies involving SD, aiming to clarify the mec...

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Main Authors: Arkadiusz Jaworski, Michał Szyszka, Karolina Brzostek, Jakub Sobieraj, Wiktoria Lewicka, Weronika Misiąg-Marmura, Konrad Szaliński, Pola Soczomska, Małgorzata Stopa, Izabella Sośniak
Format: Article
Language:English
Published: Kazimierz Wielki University 2025-07-01
Series:Journal of Education, Health and Sport
Subjects:
Sleep deprivation
serotonin
dopamine
brain derived neurotrophic factor
depressive disorder
Circadian rhythm
Online Access:https://apcz.umk.pl/JEHS/article/view/61758
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