Mutation of the conserved late element in geminivirus CP promoters abolishes Arabidopsis TCP24 transcription factor binding and decreases H3K27me3 levels on viral chromatin.

Mutation of the conserved late element in geminivirus CP promoters abolishes Arabidopsis TCP24 transcription factor binding and decreases H3K27me3 levels on viral chromatin.

In geminiviruses belonging to the genus Begomovirus, coat protein (CP) expression depends on viral AL2 protein, which derepresses and activates the CP promoter through sequence elements that lie within the viral intergenic region (IR). However, AL2 does not exhibit sequence-specific DNA binding acti...

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Main Authors: Jacqueline Williams, Elizabeth Regedanz, Natalia Lucinda, Alba Ruth Nava Fereira, Gabriela Lacatus, Mary Berger, Nels O'Connell, Tami Coursey, Jianhua Ruan, David M Bisaro, Garry Sunter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012399
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https://doi.org/10.1371/journal.ppat.1012399

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