Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged Jaundice

Background: Our objective is to find out the prevalence of urinary tract infections (UTI) among neonates with prolonged jaundice, and to review their clinical characteristics, causative microorganisms, treatment used, and underlying renal structural abnormalities.Methods: This is a retrospective cro...

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Main Authors: Jumana Albaramki, Waheed Hammad, Tamer Barakat, Mohammad Al-Sanouri, Awwab Hammad, Fareed Ahmad
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-07-01
Series:Iranian Journal of Neonatology
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Online Access:https://ijn.mums.ac.ir/article_26178_c32e69869278372883752e6da0f2636c.pdf
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Summary:Background: Our objective is to find out the prevalence of urinary tract infections (UTI) among neonates with prolonged jaundice, and to review their clinical characteristics, causative microorganisms, treatment used, and underlying renal structural abnormalities.Methods: This is a retrospective cross-sectional study of neonates with prolonged jaundice over a 5-year period at Jordan University Hospital. The study included term and preterm neonates less than 5 weeks of age with prolonged hyperbilirubinemia which was defined as persistent elevation of serum bilirubin of more than 8 mg/dl in term neonates more than two weeks of age and more than three weeks for the preterm neonates.Results: 280 newborns had prolonged jaundice and the majority were full term. The two most common causes for prolonged jaundice were urinary tract infection and breast milk jaundice. The prevalence of urinary tract infection in our study was high, reaching 33.9 %. Escherichia coli was the most common organism in neonates with UTI. Renal anomalies were detected in 9.5%. In term neonates, the mean age of presentation and the highest bilirubin levels recorded were significantly higher in neoantes with prolonged jaundice caused by UTI compared to other cause of prolonged jaundice (p<0.05).Conclusion: Our study showed a high rate of UTI in neonates with prolonged jaundice especially in preterm neonates which necessitates appropriate screening and management of UTI in prolonged jaundiced neonates.
ISSN:2251-7510
2322-2158